Synonyms: Hexamethylenediamine; 1,6-diaminohexane, HMDA
CAS No.: 124-09-4
Molecular Weight: 116.21
Chemical Formula: NH2(CH2)6NH2 in H2O
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Hexamethylenediamine 124-09-4 70% Yes Water 7732-18-5 30% No
Emergency Overview
--------------------------
DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. MATERIAL IS EXTREMELY DESTRUCTIVE TO THE UPPER RESPIRATORY TRACT, EYES AND SKIN. COMBUSTIBLE LIQUID AND VAPOR.
Potential Health Effects
----------------------------------
Inhalation:
Corrosive. Extremely destructive to tissues of the mucous membranes and upper respiratory tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Inhalation may be fatal as a result of spasm inflammation and edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
Ingestion:
Corrosive. Swallowing can cause severe burns of the mouth, throat, and stomach. Can cause sore throat, vomiting, diarrhea.
Skin Contact:
Corrosive. Symptoms of redness, pain, and severe burn can occur. May cause dermatitis.
Eye Contact:
Corrosive! Vapors are irritating and may cause damage to the eyes. Contact may cause severe burns and permanent eye damage.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician immediately.
Ingestion:
DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Call a physician immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Call a physician, immediately. Wash clothing before reuse.
Eye Contact:
Immediately flush eyes with gentle but large stream of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Call a physician immediately.
Fire:
Flash point: 93C (199F) CC
Combustible Liquid and Vapor!
Explosion:
Above the flash point, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide. Water spray may be used to keep fire exposed containers cool.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Poisonous gases are produced in fire, including nitrogen oxides.
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer!
Protect against physical damage. Outside or detached storage is preferred. Inside storage should be in a standard flammable liquids storage room or cabinet. Separate from oxidizing materials. Storage and use areas should be No Smoking areas. Solution is corrosive to metal. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
1,6-Hexanediamine: ACGIH Threshold Limit Value (TLV):
0.5 ppm (TWA) 2.3 mg/m3 (TWA).
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a half-face respirator with an organic vapor cartridge and particulate filter (NIOSH type N95 or better filter) may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece respirator with an organic vapor cartridge and particulate filter (NIOSH N 100 filter) may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P particulate filter. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres. This compound possibly exists in both particulate and vapor phase. A gas/vapor cartridge should be used in addition to the particulate filter (NIOSH type N95 or better filter). If the vapor concentration alone exceeds the exposure limits, use a supplied air respirator, because warning properties are unknown for these compounds. Breathing air quality must meet the requirements of the OSHA respiratory protection standard (29CFR1910.134).
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
Clear, colorless to yellow liquid.
Odor:
Odor of piperidine (weak fishy odor).
Solubility:
Freely soluble.
Specific Gravity:
(70% soln) 0.933 at 20C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
No information found.
Melting Point:
No information found.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage. Absorbs water and carbon dioxide from air. Vaporizes readily.
Hazardous Decomposition Products:
Burning may produce ammonia, carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Oxidizers, strong acids, acid chlorides, acid anhydrides and carbon dioxide. When dissolved in water it is a base (corrosive), reacts with acids and is corrosive towards aluminum, zinc.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
1,6-Hexanediamine: Oral rat LD50: 750 mg/kg; skin rabbit LD50: 1110 mg/kg; investigated as a reproductive effector
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Hexamethylenediamine (124-09-4) No No None
Water (7732-18-5) No No None
Environmental Fate:
When released into water, this material may biodegrade to a moderate extent.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: HEXAMETHYLENEDIAMINE SOLUTION
Hazard Class: 8
UN/NA: UN1783
Packing Group: II
Information reported for product/size: 1KG
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: HEXAMETHYLENEDIAMINE SOLUTION
Hazard Class: 8
UN/NA: UN1783
Packing Group: II
Information reported for product/size: 1KG
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Hexamethylenediamine (124-09-4) Yes Yes Yes Yes
Water (7732-18-5) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Hexamethylenediamine (124-09-4) Yes Yes No Yes
Water (7732-18-5) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Hexamethylenediamine (124-09-4) No No No No
Water (7732-18-5) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Hexamethylenediamine (124-09-4) No No No
Water (7732-18-5) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: Yes Pressure: No
Reactivity: No (Mixture / Liquid)
Australian Hazchem Code: 2R
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 3 Flammability: 2 Reactivity: 0
Label Hazard Warning:
DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. MATERIAL IS EXTREMELY DESTRUCTIVE TO THE UPPER RESPIRATORY TRACT, EYES AND SKIN. COMBUSTIBLE LIQUID AND VAPOR.
Label Precautions:
Do not breathe vapor or mist.
Do not get in eyes, on skin, or on clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat, sparks and flame.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. In all cases call a physician immediately.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 8.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)