Synonyms: Osmic acid
CAS No.: 20816-12-0
Molecular Weight: 254.20
Chemical Formula: OsO4
Product Codes:
J.T. Baker: S776
Mallinckrodt: 2768
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Osmium Tetroxide 20816-12-0 90 - 100% Yes
Emergency Overview
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DANGER! MAY BE FATAL IF SWALLOWED OR INHALED. CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 4 - Extreme (Poison)
Flammability Rating: 0 - None
Reactivity Rating: 1 - Slight
Contact Rating: 4 - Extreme (Corrosive)
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: White (Corrosive)
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Potential Health Effects
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Inhalation:
Coughing, choking, as well as headache and dizziness can occur. Pulmonary edema with a tightness in chest, dizziness, and cyanosis may occur after a 6 to 8 hour latent period. May cause kidney damage.
Ingestion:
Highly toxic. Severe burning pain in mouth, pharynx, and abdomen followed by vomiting and diarrhea of dark precipitated blood.
Skin Contact:
Toxic to skin. Severe pain and brownish or yellowish stains. Causes burns to skin as well as dermatitis and ulceration
Eye Contact:
Conjunctival edema and corneal destruction occur. Symptoms are pain, tearing, blurred vision (halos around lights) and photophobia. Eye effects can have insidious cumulative action with latent periods.
Chronic Exposure:
Long term exposure from inhalation can cause chronic coughs, broncho pneumonia,sterile lung abscess and gangrene.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or impaired respiratory function may be more susceptible to the effects of the substance.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
Fire:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
Contact with oxidizable substances may cause extremely violent combustion. In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Pick up and place in a suitable container for reclamation or disposal, using a method that does not generate dust. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from incompatible substances. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
0.002 mg/m3 (TWA) as Osmium
-ACGIH Threshold Limit Value (TLV):
0.20 ppb (TWA), 0.60 ppb (STEL) as Osmium
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus. Breathing air quality must meet the requirements of the OSHA respiratory protection standard (29CFR1910.134).
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
Colorless to pale yellow solid.
Odor:
Pungent, chlorine-like odor.
Solubility:
5.7 g/100 g water @ 10C (50F)
Specific Gravity:
4.90
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
130C (266F)
Melting Point:
ca. 40C (ca. 104F)
Vapor Density (Air=1):
8.8
Vapor Pressure (mm Hg):
7 @ 20C (68F)
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage. Substance may react violently with some organic compounds or reducing agents.
Hazardous Decomposition Products:
When heated to decomposition, emits highly toxic fumes of osmium.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Contact with hydrochloric acid causes formation of chlorine gas. A strong catalyst and contact with easily oxidized organic materials may cause fires and explosions.
Conditions to Avoid:
Heat, dusting and incompatibles.
No LD50/LC50 information found relating to normal routes of occupational exposure. Investigated as a mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Osmium Tetroxide (20816-12-0) No No None
Environmental Fate:
When released into the soil, this material is expected to readily biodegrade. When released into the soil, this material is expected to leach into groundwater.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Domestic (Land, D.O.T.)
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Proper Shipping Name: OSMIUM TETROXIDE
Hazard Class: 6.1
UN/NA: UN2471
Packing Group: I
Information reported for product/size: .5G
International (Water, I.M.O.)
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Proper Shipping Name: OSMIUM TETROXIDE
Hazard Class: 6.1
UN/NA: UN2471
Packing Group: I
Information reported for product/size: .5G
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Osmium Tetroxide (20816-12-0) Yes Yes No Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Osmium Tetroxide (20816-12-0) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Osmium Tetroxide (20816-12-0) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
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Osmium Tetroxide (20816-12-0) 1000 P087 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: 2X
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 4 Flammability: 0 Reactivity: 0
Label Hazard Warning:
DANGER! MAY BE FATAL IF SWALLOWED OR INHALED. CAUSES SEVERE IRRITATION TO EYES, SKIN AND RESPIRATORY TRACT.
Label Precautions:
Do not breathe dust.
Keep container closed.
Use only with adequate ventilation.
Avoid contact with eyes, skin and clothing.
Wash thoroughly after handling.
Label First Aid:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. If swallowed, give large quantities of water to drink and get medical attention immediately. Never give anything by mouth to an unconscious person. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 8.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)